HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: HELLS (Q9NRZ9)
Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6)
Gene: HELLS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Helicase_C, CENP-T_C~SNF2-rel_dom
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 838
+	Hs
		918062 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD7_HUMAN (31-836): 0: 657: 27.28
+	Hs
		917182 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD3_HUMAN (50-828): 0: 649: 24.79
+	Hs
		917965 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD8_HUMAN (2-836): 0: 635: 26.71
+	Hs
		846914 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMCA4_HUMAN (9-838): 0: 633: 24.89
+	Hs
		917277 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Hs
		917635 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD6_HUMAN (7-836): 0: 623: 26.56
+	Hs
		917364 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD9_HUMAN (3-836): 0: 619: 26.49
+	Hs
		229352 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMCA5_HUMAN (75-833): 0: 607: 30.76
+	Hs
		151483 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD2_HUMAN (5-830): 0: 596: 27.25
+	Sc
		356551 H4_YEAST (18-103): 6.13e-41: 132: 90.70		IRC5_YEAST (87-804): 0: 614: 38.03
+	Sp
		144535 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		HRP3_SCHPO (55-833): 0: 604: 29.51
+	Dm
		950383 H4_DROME (1-103): 4.51e-48: 150: 99.03		ISWI_DROME (101-833): 0: 584: 30.20
+	Sc
		356350 H4_YEAST (18-103): 6.13e-41: 132: 90.70		CHD1_YEAST (11-838): 0: 577: 26.00
+	Sc
		356774 H4_YEAST (18-103): 6.13e-41: 132: 90.70		ISW2_YEAST (213-805): 1.24e-126: 409: 41.21
+	Sc
		356424 H4_YEAST (18-103): 6.13e-41: 132: 90.70		ISW1_YEAST (212-772): 2e-120: 392: 41.95
+	Hs
		917533 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD1L_HUMAN (218-755): 1.8e-105: 347: 40.30
+	Sc
		356248 H4_YEAST (18-103): 6.13e-41: 132: 90.70		SNF2_YEAST (213-830): 4.29e-102: 349: 35.92
+	Sp
		194289 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		FFT3_SCHPO (226-743): 3.04e-77: 271: 33.96
+	Sc
		356315 H4_YEAST (18-103): 6.13e-41: 132: 90.70		BTAF1_YEAST (211-826): 4.38e-70: 254: 30.83