HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: ASF1B (Q9NVP2)
Histone chaperone ASF1B (Anti-silencing function protein 1 homolog B) (hAsf1) (hAsf1b) (CCG1-interacting factor A-II) (CIA-II) (hCIA-II)
Gene: ASF1B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.935

Property	Details
Experiments	28514442, 24981860, 33961781, 20953179, 23075851
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	ASF1_hist_chap~CENP-T_C
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0032991 - protein-containing complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 202
+	Gg
		917057 H4_CHICK (1-103): 1.38e-48: 151: 100.00		ASF1_CHICK (1-202): 2.03e-119: 338: 70.59
+	Hs
		918163 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		ASF1A_HUMAN (1-202): 2.03e-119: 338: 70.59
+	At
		886857 H4_ARATH (1-103): 3.47e-48: 150: 98.06		ASF1B_ARATH (1-159): 2e-88: 260: 57.86
+	Sc
		356323 H4_YEAST (18-103): 6.13e-41: 132: 90.70		ASF1_YEAST (1-158): 2.55e-86: 257: 58.23
+	Sp
		251625 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		ASF1_SCHPO (1-157): 4.05e-80: 241: 53.37