HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: CHD7 (Q9P2D1)
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)
Gene: CHD7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	27248496, 30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Helicase_C, CENP-T_C~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 2997
+	Hs
		229352 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Dm
		950383 H4_DROME (1-103): 4.51e-48: 150: 99.03		ISWI_DROME (850-1894): 0: 884: 26.45
+	Hs
		917182 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD3_HUMAN (549-1971): 0: 836: 26.40
+	Sc
		356350 H4_YEAST (18-103): 6.13e-41: 132: 90.70		CHD1_YEAST (815-1973): 0: 851: 28.88
+	Sp
		144535 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		HRP3_SCHPO (614-1971): 0: 844: 25.15
+	Hs
		917277 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD4_HUMAN (607-1892): 0: 820: 26.91
+	Hs
		151483 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD2_HUMAN (538-1907): 0: 814: 26.11
+	Sc
		356774 H4_YEAST (18-103): 6.13e-41: 132: 90.70		ISW2_YEAST (783-1895): 0: 827: 25.83
+	Sc
		356424 H4_YEAST (18-103): 6.13e-41: 132: 90.70		ISW1_YEAST (822-1900): 0: 818: 26.26
+	Hs
		846914 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMCA4_HUMAN (232-1604): 0: 790: 22.42
+	Hs
		917364 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD9_HUMAN (2255-2982): 0: 724: 39.00
+	Hs
		917635 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD6_HUMAN (2109-2989): 0: 691: 29.39
+	Hs
		917965 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD8_HUMAN (1-976): 4.16e-09: 65.1: 7.67