HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: MLX (Q9UH92)
Max-like protein X (Class D basic helix-loop-helix protein 13) (bHLHd13) (Max-like bHLHZip protein) (Protein BigMax) (Transcription factor-like protein 4)
Gene: MLX

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 298
+	Hs
		917953 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MLXIP_HUMAN (61-294): 1.84e-68: 230: 27.20
+	Hs
		917972 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MLXPL_HUMAN (44-293): 1.23e-62: 214: 28.52
+	Hs
		607804 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		USF1_HUMAN (37-230): 4.33e-38: 138: 18.91
+	Hs
		917336 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		USF2_HUMAN (15-236): 8.82e-38: 138: 20.08
+	Mm
		348414 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		MYC_MOUSE (31-217): 3.64e-35: 133: 19.68
+	Hs
		346438 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYC_HUMAN (31-217): 1.72e-34: 131: 19.15
+	Hs
		379230 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYCN_HUMAN (43-214): 2.1e-31: 123: 17.44
+	Hs
		585112 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TFEB_HUMAN (75-236): 2.76e-28: 115: 17.92
+	Hs
		252913 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MITF_HUMAN (116-236): 9.82e-24: 102: 17.42
+	Hs
		585646 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TFE3_HUMAN (48-229): 9.12e-24: 102: 14.84
+	Mm
		918249 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		TFE3_MOUSE (48-229): 9.59e-24: 102: 14.29
+	Hs
		917430 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		USF3_HUMAN (113-241): 1.03e-22: 100: 16.30
+	Hs
		738952 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SRBP1_HUMAN (66-217): 1.11e-22: 99: 19.23
+	Hs
		379768 H4G_HUMAN (1-98): 1.04e-38: 126: 84.69		MYCN_HUMAN (43-214): 2.1e-31: 123: 17.44
+	Hs
		898095 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MAX_HUMAN (109-223): 1.57e-22: 93.4: 24.35
+	Hs
		917131 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TFAP4_HUMAN (114-208): 4.8e-21: 93: 26.32
+	Sc
		356366 H4_YEAST (18-103): 6.13e-41: 132: 90.70		TYE7_YEAST (36-210): 5.38e-27: 108: 19.43
+	Sc
		356426 H4_YEAST (18-103): 6.13e-41: 132: 90.70		RTG3_YEAST (66-236): 1.06e-24: 105: 20.77