HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: PHF8 (Q9UPP1)
Histone lysine demethylase PHF8 (EC 1.14.11.27) (EC 1.14.11.65) (PHD finger protein 8) ([histone H3]-dimethyl-L-lysine(36) demethylase PHF8) ([histone H3]-dimethyl-L-lysine(9) demethylase PHF8)
Gene: PHF8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	30804502, 20622853
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 1060
+	Hs
		256395 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		PHF2_HUMAN (37-1060): 0: 1122: 46.37
+	Hs
		918168 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KDM2A_HUMAN (90-901): 0: 622: 25.09
+	Hs
		917624 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KDM2B_HUMAN (75-968): 0: 601: 24.09
+	Sc
		356496 H4_YEAST (18-103): 6.13e-41: 132: 90.70		JHD1_YEAST (37-404): 3.4e-136: 422: 29.04
+	Hs
		917179 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BPTF_HUMAN (30-153): 6.03e-29: 128: 22.40
+	Hs
		918055 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CXXC1_HUMAN (11-145): 9.34e-28: 122: 25.93
+	Dm
		950422 H4_DROME (1-103): 4.51e-48: 150: 99.03		NU301_DROME (4-97): 6.65e-19: 95.4: 27.84
+	Hs
		917843 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		DIDO1_HUMAN (41-92): 9.31e-11: 68.6: 46.43