HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: SP16H (Q9Y5B9)
FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)
Gene: SUPT16H

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.939

Property	Details
Experiments	35320725, 28514442, 27248496, 30804502, 33961781, 37071682
Identification Methods	pull down, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	CENP-T_C~Rtt106
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 1047
+	Sp
		292838 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		SPT16_SCHPO (3-1016): 0: 1010: 37.43
+	Sc
		356335 H4_YEAST (18-103): 6.13e-41: 132: 90.70		SPT16_YEAST (3-1008): 0: 938: 33.49
+	Sc
		356547 H4_YEAST (18-103): 6.13e-41: 132: 90.70		YFH6_YEAST (6-428): 9.61e-74: 255: 13.25