HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: NCOA3 (Q9Y6Q9)
Nuclear receptor coactivator 3 (NCoA-3) (EC 2.3.1.48) (ACTR) (Amplified in breast cancer 1 protein) (AIB-1) (CBP-interacting protein) (pCIP) (Class E basic helix-loop-helix protein 42) (bHLHe42) (Receptor-associated coactivator 3) (RAC-3) (Steroid receptor coactivator protein 3) (SRC-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1)
Gene: NCOA3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	14747462, 11163245
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 1424
+	Hs
		917350 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HIF1A_HUMAN (1-829): 3.49e-114: 381: 14.72
+	Hs
		917325 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		NCOA2_HUMAN (1-1422): 5.82e-99: 350: 38.89
+	Hs
		126120 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BMAL1_HUMAN (6-541): 4.9e-105: 349: 18.23
+	Mm
		139862 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		CLOCK_MOUSE (1-779): 3.86e-79: 282: 13.65
+	Hs
		181511 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CLOCK_HUMAN (1-791): 2.47e-78: 279: 13.73
+	Hs
		649080 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		ARNT_HUMAN (6-642): 2.95e-76: 272: 16.01
+	Hs
		917621 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KMT2C_HUMAN (471-1383): 2.87e-11: 70.9: 12.87