HitPredict

Interactor 1: H4 (P62806)
Histone H4
Gene: H4c1

Interactor 2: HDAC2 (P70288)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-) (YY1 transcription factor-binding protein)
Gene: HDAC2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	22441348
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 103 Mm			1 488
+	Hs
		917682 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HDAC2_HUMAN (1-488): 0: 707: 99.39
+	Dm
		950398 H4_DROME (1-103): 4.51e-48: 150: 99.03		HDAC1_DROME (5-472): 0: 654: 77.71
+	Mm
		140249 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		HDAC1_MOUSE (1-446): 0: 647: 89.46
+	Hs
		917226 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HDAC1_HUMAN (1-446): 0: 643: 89.24
+	At
		886854 H4_ARATH (1-103): 3.47e-48: 150: 98.06		HDA6_ARATH (1-467): 0: 580: 57.02
+	Hs
		177252 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HDAC3_HUMAN (10-431): 0: 575: 58.02
+	Sc
		356336 H4_YEAST (18-103): 6.13e-41: 132: 90.70		RPD3_YEAST (5-422): 0: 578: 60.71
+	Sp
		140573 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		PHD1_SCHPO (7-411): 0: 519: 52.56
+	Sc
		356604 H4_YEAST (18-103): 6.13e-41: 132: 90.70		HOS2_YEAST (11-430): 8.29e-174: 498: 46.95
+	Hs
		917872 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HDAC8_HUMAN (33-372): 1.01e-137: 403: 43.40
+	Sc
		356643 H4_YEAST (18-103): 6.13e-41: 132: 90.70		HDA1_YEAST (9-330): 9.34e-122: 373: 27.56
+	Hs
		918077 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HDAC6_HUMAN (11-363): 7.53e-102: 332: 24.04