HitPredict

Interactor 1: H4 (P62806)
Histone H4
Gene: H4c1

Interactor 2: CBX1 (P83917)
Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein)
Gene: CBX1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29795351
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 103 Mm			1 185
+	Hs
		917205 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		917108 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00
+	Hs
		800335 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Mm
		918248 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		CBX5_MOUSE (1-183): 7.63e-60: 186: 57.98
+	Hs
		327834 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX7_HUMAN (12-114): 5.3e-30: 112: 27.18
+	Mm
		918268 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		CBX6_MOUSE (12-101): 2.46e-27: 107: 30.00
+	Mm
		918259 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		CBX7_MOUSE (12-106): 5.6e-28: 104: 27.37
+	Hs
		315996 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX6_HUMAN (12-101): 1.25e-25: 103: 30.00
+	Hs
		917274 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX2_HUMAN (10-110): 2.55e-25: 103: 29.70
+	Hs
		918158 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CDYL_HUMAN (7-120): 2.53e-25: 103: 25.86
+	Hs
		123221 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX4_HUMAN (12-89): 1e-24: 101: 34.62
+	Hs
		917958 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX8_HUMAN (12-88): 1.45e-24: 100: 35.07
+	Hs
		918227 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CDY2_HUMAN (18-110): 2.53e-23: 97.9: 25.00
+	Dm
		639958 H4_DROME (1-103): 4.51e-48: 150: 99.03		PC_DROME (2-80): 1.9e-14: 72.2: 35.44