HitPredict

Interactor 1: H4 (P62806)
Histone H4
Gene: H4c1

Interactor 2: CBX5 (Q61686)
Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	29795351, 11571267
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 103 Mm			1 191
+	Hs
		800335 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX5_HUMAN (1-191): 2.88e-69: 210: 97.91
+	Hs
		917205 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX3_HUMAN (1-181): 4.97e-62: 192: 60.22
+	Hs
		917108 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX1_HUMAN (26-180): 3.2e-56: 177: 64.74
+	Mm
		918238 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		CBX1_MOUSE (26-180): 3.2e-56: 177: 64.74
+	Hs
		327834 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX7_HUMAN (11-190): 7.01e-45: 150: 24.31
+	Hs
		918158 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CDYL_HUMAN (8-159): 2.83e-30: 117: 23.13
+	Hs
		123221 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX4_HUMAN (11-125): 2.1e-27: 109: 25.22
+	Mm
		918268 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		CBX6_MOUSE (11-119): 2.46e-27: 108: 25.98
+	Hs
		918227 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CDY2_HUMAN (17-121): 1.19e-25: 104: 25.69
+	Hs
		917274 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX2_HUMAN (10-109): 8.73e-25: 102: 32.00
+	Mm
		918259 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		CBX7_MOUSE (11-97): 3.26e-27: 102: 29.89
+	Hs
		315996 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX6_HUMAN (11-119): 5.27e-25: 101: 25.98
+	Hs
		917958 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX8_HUMAN (11-88): 8.14e-25: 100: 34.62