HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned2173
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 217
+	Hs
		924623 H2B2F_HUMAN (1-126): 2.21e-54: 168: 98.41		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924820 H2B1M_HUMAN (1-126): 4.46e-54: 167: 96.83		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		241496 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		883010 H2BFS_HUMAN (1-126): 1.03e-53: 166: 97.62		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924770 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		886077 H2B1D_HUMAN (1-126): 3.24e-53: 164: 99.21		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924819 H2B1N_HUMAN (1-126): 3e-53: 164: 99.21		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924821 H2B1L_HUMAN (1-126): 2.18e-52: 163: 98.41		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		411752 H2B2F_HUMAN (1-126): 2.21e-54: 168: 98.41		LCK_HUMAN (3-202): 3.69e-37: 137: 28.91
+	Hs
		411835 H2B1M_HUMAN (1-126): 4.46e-54: 167: 96.83		LCK_HUMAN (3-202): 3.69e-37: 137: 28.91
+	Hs
		411664 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		LCK_HUMAN (3-202): 3.69e-37: 137: 28.91
+	Hs
		411813 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		LCK_HUMAN (3-202): 3.69e-37: 137: 28.91
+	Hs
		411656 H2B1D_HUMAN (1-126): 3.24e-53: 164: 99.21		LCK_HUMAN (3-202): 3.69e-37: 137: 28.91
+	Hs
		411834 H2B1N_HUMAN (1-126): 3e-53: 164: 99.21		LCK_HUMAN (3-202): 3.69e-37: 137: 28.91
+	Hs
		411836 H2B1L_HUMAN (1-126): 2.18e-52: 163: 98.41		LCK_HUMAN (3-202): 3.69e-37: 137: 28.91
+	Hs
		557845 U3KQK0_HUMAN (1-126): 3.61e-55: 171: 99.21		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14
+	Hs
		557647 H2B1D_HUMAN (1-126): 3.24e-53: 164: 99.21		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14
+	Hs
		557738 H2B3B_HUMAN (1-126): 8.29e-52: 161: 95.24		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14