HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: NOLC1 (Q14978)
Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130)
Gene: NOLC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 699
+	Hs
		241507 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		TOP2B_HUMAN (6-463): 1.53e-66: 241: 14.13
+	Hs
		918302 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		TOP2B_HUMAN (6-463): 1.53e-66: 241: 14.13
+	Hs
		973343 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		TOP2B_HUMAN (6-463): 1.53e-66: 241: 14.13
+	Hs
		241529 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		NOLC1_HUMAN (1-699): 6.47e-68: 237: 100.00
+	Hs
		241433 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Hs
		420797 H2B1J_HUMAN (1-126): 6.62e-54: 166: 98.41		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Hs
		508918 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Hs
		509018 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Hs
		509080 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44
+	Hs
		918628 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		MINT_HUMAN (28-674): 3.38e-12: 72.4: 11.90
+	Hs
		1129830 H2B2F_HUMAN (1-126): 2.21e-54: 168: 98.41		TITIN_HUMAN (8-622): 2.9e-11: 69.6: 12.44
+	Hs
		617962 H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41		TITIN_HUMAN (8-622): 2.9e-11: 69.6: 12.44
+	Hs
		1087299 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		TITIN_HUMAN (8-622): 2.9e-11: 69.6: 12.44
+	Hs
		1264778 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		TITIN_HUMAN (8-622): 2.9e-11: 69.6: 12.44
+	Hs
		241595 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		TITIN_HUMAN (8-622): 2.9e-11: 69.6: 12.44
+	Hs
		883041 H2BFS_HUMAN (1-126): 1.03e-53: 166: 97.62		TITIN_HUMAN (8-622): 2.9e-11: 69.6: 12.44
+	Hs
		918561 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		TITIN_HUMAN (8-622): 2.9e-11: 69.6: 12.44
+	Hs
		1087196 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		NIPBL_HUMAN (62-535): 1.22e-09: 63.9: 13.77
+	Hs
		918442 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		NIPBL_HUMAN (62-535): 1.22e-09: 63.9: 13.77
+	Hs
		241581 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64