HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: SRCAP (Q6ZRS2)
Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator)
Gene: SRCAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	25281560, 34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 3230
+	Hs
		1087210 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		SRCAP_HUMAN (1-3230): 0: 1210: 100.00
+	Hs
		1059648 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		CHD4_HUMAN (1959-2633): 3.48e-89: 328: 19.60
+	Hs
		1059777 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		CHD4_HUMAN (1959-2633): 3.48e-89: 328: 19.60
+	Hs
		241527 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		CHD4_HUMAN (1959-2633): 3.48e-89: 328: 19.60
+	Hs
		918368 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		CHD4_HUMAN (1959-2633): 3.48e-89: 328: 19.60
+	Hs
		658646 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		SMCA1_HUMAN (2003-2406): 8.09e-92: 327: 26.49
+	Hs
		658684 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		SMCA1_HUMAN (2003-2406): 8.09e-92: 327: 26.49
+	Hs
		241591 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		CHD5_HUMAN (1995-2642): 4.91e-88: 324: 19.69
+	Hs
		918541 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		CHD5_HUMAN (1995-2642): 4.91e-88: 324: 19.69
+	Hs
		229353 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		SMCA5_HUMAN (2003-2357): 1.13e-90: 323: 28.77
+	Hs
		229415 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		SMCA5_HUMAN (2003-2357): 1.13e-90: 323: 28.77
+	Hs
		229458 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		SMCA5_HUMAN (2003-2357): 1.13e-90: 323: 28.77
+	Hs
		1307128 H2B1M_HUMAN (1-126): 4.46e-54: 167: 96.83		CHD8_HUMAN (2021-2361): 3.76e-67: 256: 28.57
+	Hs
		1087418 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		CHD8_HUMAN (2021-2361): 3.76e-67: 256: 28.57
+	Hs
		918705 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		CHD8_HUMAN (2021-2361): 3.76e-67: 256: 28.57
+	Hs
		846915 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		SMCA4_HUMAN (1505-1858): 9.38e-13: 76.9: 13.22
+	Hs
		846990 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		SMCA4_HUMAN (1505-1858): 9.38e-13: 76.9: 13.22
+	Hs
		1087343 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		EP400_HUMAN (1085-1716): 1.74e-11: 73: 13.39
+	Hs
		918613 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		EP400_HUMAN (1085-1716): 1.74e-11: 73: 13.39
+	Hs
		846736 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		SMCA2_HUMAN (1477-1770): 8.82e-09: 63.8: 11.91