HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: HDGR2 (Q7Z4V5)
Hepatoma-derived growth factor-related protein 2 (HDGF-related protein 2) (HRP-2) (Hepatoma-derived growth factor 2) (HDGF-2)
Gene: HDGFL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 671
+	Hs
		1274410 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		NSD1_HUMAN (2-668): 2.86e-90: 310: 12.29
+	Hs
		918612 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		NSD1_HUMAN (2-668): 2.86e-90: 310: 12.29
+	Hs
		1190696 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		HDGR2_HUMAN (1-671): 9.52e-82: 274: 100.00
+	Hs
		331768 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		NSD2_HUMAN (3-440): 5.42e-66: 238: 11.70
+	Hs
		331825 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		NSD2_HUMAN (3-440): 5.42e-66: 238: 11.70
+	Hs
		918663 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		NSD3_HUMAN (4-413): 2.6e-62: 227: 11.66
+	Hs
		265986 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		PSIP1_HUMAN (1-553): 1.35e-54: 197: 23.49
+	Hs
		266023 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		PSIP1_HUMAN (1-553): 1.35e-54: 197: 23.49
+	Hs
		266045 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		PSIP1_HUMAN (1-553): 1.35e-54: 197: 23.49
+	Hs
		855491 H2B2F_HUMAN (1-126): 2.21e-54: 168: 98.41		MSH6_HUMAN (4-299): 4.35e-45: 175: 12.98
+	Hs
		855449 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		MSH6_HUMAN (4-299): 4.35e-45: 175: 12.98
+	Hs
		855488 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		MSH6_HUMAN (4-299): 4.35e-45: 175: 12.98
+	Hs
		918769 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		ZMYD8_HUMAN (6-605): 7.73e-40: 159: 14.24
+	Hs
		1087155 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		GLYR1_HUMAN (6-212): 3.25e-36: 145: 21.10
+	Hs
		918404 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		GLYR1_HUMAN (6-212): 3.25e-36: 145: 21.10
+	Hs
		241483 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		HDGF_HUMAN (3-234): 8.81e-26: 108: 35.78
+	Hs
		850890 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		HDGF_HUMAN (3-234): 8.81e-26: 108: 35.78
+	Hs
		850932 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		HDGF_HUMAN (3-234): 8.81e-26: 108: 35.78
+	Hs
		1087196 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		NIPBL_HUMAN (100-662): 1.42e-17: 89.7: 16.10
+	Hs
		918442 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		NIPBL_HUMAN (100-662): 1.42e-17: 89.7: 16.10