HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: UBP48 (Q86UV5)
Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48)
Gene: USP48

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	25281560, 34079125, 33903120
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 1035
+	Hs
		420851 H2B1J_HUMAN (1-126): 6.62e-54: 166: 98.41		UBP48_HUMAN (1-1035): 0: 1274: 100.00
+	Hs
		707674 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		UBP48_HUMAN (1-1035): 0: 1274: 100.00
+	Mm
		500577 H2B1F_MOUSE (1-126): 7.96e-53: 164: 99.21		UBP48_MOUSE (1-1035): 0: 1245: 92.03
+	Hs
		241654 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		UBP36_HUMAN (15-525): 2.42e-103: 351: 18.10
+	Dm
		355274 H2B_DROME (36-126): 9.18e-47: 148: 94.51		UBP7_DROME (81-487): 9.74e-110: 369: 26.28
+	Hs
		420891 H2B1J_HUMAN (1-126): 6.62e-54: 166: 98.41		UBP36_HUMAN (15-525): 2.42e-103: 351: 18.10
+	Hs
		707772 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		UBP36_HUMAN (15-525): 2.42e-103: 351: 18.10
+	Hs
		1087318 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		UBP7_HUMAN (66-487): 5.02e-100: 341: 26.05
+	Hs
		707705 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		UBP7_HUMAN (66-487): 5.02e-100: 341: 26.05
+	Hs
		1231220 H2B3B_HUMAN (1-126): 8.29e-52: 161: 95.24		UBP7_HUMAN (66-487): 5.02e-100: 341: 26.05
+	Hs
		259286 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		UBP12_HUMAN (54-422): 1.09e-100: 323: 22.42
+	Hs
		905383 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		UBP46_HUMAN (54-421): 7.22e-101: 323: 22.73
+	Hs
		905394 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		UBP46_HUMAN (54-421): 7.22e-101: 323: 22.73
+	Hs
		1087411 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		UBP42_HUMAN (45-435): 1.3e-91: 321: 20.40
+	Hs
		271037 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		UBP2_HUMAN (38-425): 1.46e-95: 317: 20.98
+	Hs
		918801 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		UBP3_HUMAN (12-430): 3.93e-96: 316: 19.38
+	Hs
		707807 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		UBP3_HUMAN (12-430): 3.93e-96: 316: 19.38
+	Hs
		1087489 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		UBP22_HUMAN (16-400): 5.16e-95: 313: 19.38
+	Hs
		707794 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		UBP22_HUMAN (16-400): 5.16e-95: 313: 19.38
+	Hs
		1087499 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		UBP20_HUMAN (21-199): 3.28e-29: 128: 17.44