HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: CHD7 (Q9P2D1)
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)
Gene: CHD7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 2997
+	Hs
		229353 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Hs
		229415 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Hs
		229458 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		SMCA5_HUMAN (856-1893): 0: 928: 27.39
+	Hs
		658646 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		SMCA1_HUMAN (812-1864): 0: 922: 26.51
+	Hs
		658684 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		SMCA1_HUMAN (812-1864): 0: 922: 26.51
+	Hs
		241591 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		CHD5_HUMAN (670-1947): 0: 837: 25.68
+	Hs
		918541 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		CHD5_HUMAN (670-1947): 0: 837: 25.68
+	Hs
		1018625 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		CHD3_HUMAN (549-1971): 0: 836: 26.40
+	Hs
		241517 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		CHD3_HUMAN (549-1971): 0: 836: 26.40
+	Hs
		918325 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		CHD3_HUMAN (549-1971): 0: 836: 26.40
+	Hs
		151395 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		CHD1_HUMAN (650-1969): 0: 824: 25.71
+	Hs
		1059648 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		CHD4_HUMAN (607-1892): 0: 820: 26.91
+	Hs
		1059777 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		CHD4_HUMAN (607-1892): 0: 820: 26.91
+	Hs
		241527 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		CHD4_HUMAN (607-1892): 0: 820: 26.91
+	Hs
		918368 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		CHD4_HUMAN (607-1892): 0: 820: 26.91
+	Hs
		846915 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		SMCA4_HUMAN (232-1604): 0: 790: 22.42
+	Hs
		846990 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		SMCA4_HUMAN (232-1604): 0: 790: 22.42
+	Hs
		918540 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		CHD6_HUMAN (2109-2989): 0: 691: 29.39
+	Hs
		1307128 H2B1M_HUMAN (1-126): 4.46e-54: 167: 96.83		CHD8_HUMAN (1-976): 4.16e-09: 65.1: 7.67
+	Hs
		918705 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		CHD8_HUMAN (1-976): 4.16e-09: 65.1: 7.67