HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: HMGX4 (Q9UGU5)
HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)
Gene: HMGXB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 37071682
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 601
+	Hs
		1087463 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		HMGX4_HUMAN (1-601): 0: 813: 100.00
+	Hs
		297497 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		TOX4_HUMAN (339-528): 4.7e-37: 148: 24.76
+	Hs
		1087228 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Hs
		918481 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Hs
		707673 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Hs
		420830 H2B1J_HUMAN (1-126): 6.62e-54: 166: 98.41		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		918316 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		996694 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		996812 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		996768 H2B3B_HUMAN (1-126): 8.29e-52: 161: 95.24		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		996816 H2B1A_HUMAN (1-126): 3.14e-46: 147: 84.25		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		449786 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		HMGB1_HUMAN (388-485): 1.57e-24: 103: 30.00
+	Hs
		643302 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		HMGB2_HUMAN (405-494): 1.76e-22: 97.6: 35.56
+	Hs
		643380 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		HMGB2_HUMAN (405-494): 1.76e-22: 97.6: 35.56
+	Hs
		643248 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		HMGB2_HUMAN (405-494): 1.76e-22: 97.6: 35.56
+	Hs
		241615 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		175767 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		HMGB3_HUMAN (411-495): 5.79e-12: 67.2: 21.84
+	Sc
		355756 H2B2_YEAST (3-125): 5.51e-37: 124: 71.55		NHP6B_YEAST (388-479): 1.39e-15: 74.5: 28.72
+	Sc
		355755 H2B2_YEAST (3-125): 5.51e-37: 124: 71.55		NHP6A_YEAST (394-476): 2.15e-14: 71: 29.41
+	Sc
		355313 H2B1_YEAST (3-125): 1.92e-36: 122: 71.55		NHP6A_YEAST (394-476): 2.15e-14: 71: 29.41