HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: TPX2 (Q9ULW0)
Targeting protein for Xklp2 (Differentially expressed in cancerous and non-cancerous lung cells 2) (DIL-2) (Hepatocellular carcinoma-associated antigen 519) (Hepatocellular carcinoma-associated antigen 90) (Protein fls353) (Restricted expression proliferation-associated protein 100) (p100)
Gene: TPX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25281560, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 747
+	Hs
		1087481 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Hs
		707788 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		TPX2_HUMAN (1-747): 2.4e-154: 468: 100.00
+	Hs
		1129830 H2B2F_HUMAN (1-126): 2.21e-54: 168: 98.41		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90
+	Hs
		617962 H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90
+	Hs
		1087299 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90
+	Hs
		1264778 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90
+	Hs
		241595 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90
+	Hs
		883041 H2BFS_HUMAN (1-126): 1.03e-53: 166: 97.62		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90
+	Hs
		918561 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90
+	Hs
		886166 H2B1D_HUMAN (1-126): 3.24e-53: 164: 99.21		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90
+	Hs
		1264792 H2B1L_HUMAN (1-126): 2.18e-52: 163: 98.41		TITIN_HUMAN (55-725): 1e-09: 64.5: 11.90