HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: SP16H (Q9Y5B9)
FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)
Gene: SUPT16H

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	34079125, 33961781, 37071682
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Rtt106
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 1047
+	Hs
		1087510 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1274488 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		420898 H2B1J_HUMAN (1-126): 6.62e-54: 166: 98.41		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		707803 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1231268 H2B3B_HUMAN (1-126): 8.29e-52: 161: 95.24		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1282986 H2B1A_HUMAN (1-126): 3.14e-46: 147: 84.25		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Sc
		355829 H2B2_YEAST (3-125): 5.51e-37: 124: 71.55		SPT16_YEAST (3-1008): 0: 938: 33.49
+	Sc
		355400 H2B1_YEAST (3-125): 1.92e-36: 122: 71.55		SPT16_YEAST (3-1008): 0: 938: 33.49