HitPredict

Interactor 1: RAB3C (P62824)
Ras-related protein Rab-3C
Gene: RAB3C

Interactor 2: RIMS2 (Q9JIS1)
Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2)
Gene: RIMS2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	10748113
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	FYVE_2~Ras, PDZ~Ras
Common GO terms	GO:0017157 - regulation of exocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 227 Rn			1 1555
+	Rn
		926103 RAB3A_RAT (9-227): 2.43e-88: 261: 82.73		RIMS2_RAT (1-1555): 0: 910: 100.00
+	Hs
		914274 RB11A_HUMAN (20-227): 4.3e-99: 288: 35.85		SYTL4_HUMAN (1002-1551): 4.91e-46: 179: 12.55
+	Hs
		1134943 RAB1B_HUMAN (23-227): 8.8e-90: 264: 41.95		SYT6_HUMAN (1159-1527): 1.48e-47: 180: 17.26
+	Hs
		591484 RAB3A_HUMAN (9-227): 3.93e-88: 261: 82.73		SYTL4_HUMAN (1002-1551): 4.91e-46: 179: 12.55
+	Mm
		812771 RAB3C_MOUSE (1-227): 6.33e-95: 278: 100.00		RP3A_MOUSE (1023-1543): 2.5e-32: 137: 11.52
+	Mm
		722679 RAB3D_MOUSE (9-227): 4.64e-90: 266: 75.34		RP3A_MOUSE (1023-1543): 2.5e-32: 137: 11.52
+	Mm
		812772 RAB3A_MOUSE (9-227): 2.43e-88: 261: 82.73		RP3A_MOUSE (1023-1543): 2.5e-32: 137: 11.52
+	Hs
		591501 RAB3A_HUMAN (9-227): 3.93e-88: 261: 82.73		RP3A_HUMAN (1027-1543): 9.15e-31: 132: 12.96
+	Rn
		812780 RAB3A_RAT (9-227): 2.43e-88: 261: 82.73		RP3A_RAT (1023-1543): 4.52e-30: 130: 11.29
+	Hs
		914240 RB11A_HUMAN (20-227): 4.3e-99: 288: 35.85		SYTL5_HUMAN (978-1504): 2.4e-20: 99.7: 11.55
+	Hs
		914318 RB11A_HUMAN (20-227): 4.3e-99: 288: 35.85		ESYT1_HUMAN (687-877): 4.54e-19: 96.2: 22.92
+	Mm
		919021 RAB3C_MOUSE (1-227): 6.33e-95: 278: 100.00		RIMS1_MOUSE (166-883): 1.52e-15: 85.1: 14.11
+	Hs
		591482 RAB3A_HUMAN (9-227): 3.93e-88: 261: 82.73		SYTL5_HUMAN (978-1504): 2.4e-20: 99.7: 11.55
+	Ce
		1094851 RAB3_CAEEL (9-227): 6.47e-89: 262: 73.52		RIM_CAEEL (885-1514): 6.33e-19: 95.8: 11.27
+	Mm
		919024 RAB3C_MOUSE (1-227): 6.33e-95: 278: 100.00		RIMS2_MOUSE (151-883): 6.7e-13: 76.2: 13.08
+	Mm
		722691 RAB3D_MOUSE (9-227): 4.64e-90: 266: 75.34		RIMS1_MOUSE (166-883): 1.52e-15: 85.1: 14.11
+	Mm
		926089 RAB3A_MOUSE (9-227): 2.43e-88: 261: 82.73		RIMS1_MOUSE (166-883): 1.52e-15: 85.1: 14.11
+	Mm
		722693 RAB3D_MOUSE (9-227): 4.64e-90: 266: 75.34		RIMS2_MOUSE (151-883): 6.7e-13: 76.2: 13.08
+	Mm
		926097 RAB3A_MOUSE (9-227): 2.43e-88: 261: 82.73		RIMS2_MOUSE (151-883): 6.7e-13: 76.2: 13.08
+	Hs
		591478 RAB3A_HUMAN (9-227): 3.93e-88: 261: 82.73		RIMS1_HUMAN (169-883): 4.39e-12: 73.5: 14.93