Interactor 1: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Interactor 2: IMB1 (Q14974)
Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)
Gene: KPNB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35271311, 23729730, 10037787, 11024021, 10944119, 9214382, 26496610, 9135132, 9102465, 10779340, 35235311, 20658144, 8909533, 9045717
Identification Methods affinity chromatography technology, pull down, far western blotting, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains IBN_N~Ras
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
and 7 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 216
Hs

1 876
+ At
+ At
+ At
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ At
+ Sc
+ Dm
+ Sc
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024