HitPredict

Interactor 1: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Interactor 2: NUP54 (Q7Z3B4)
Nucleoporin p54 (54 kDa nucleoporin)
Gene: NUP54

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	35271311, 32814053
Identification Methods	affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 507
+	Hs
		727236 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		NU214_HUMAN (7-179): 1.39e-17: 88.5: 16.04
+	Sc
		698833 GSP1_YEAST (1-214): 5.23e-83: 247: 80.56		NU159_YEAST (44-283): 8.5e-10: 63.5: 10.36
+	Hs
		857959 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		NUP98_HUMAN (2-257): 4.92e-12: 70.8: 15.44