HitPredict

Interactor 1: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29509190, 21951318
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 530
+	Hs
		1070333 RAB35_HUMAN (6-188): 1.31e-87: 258: 29.19		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		918924 RAB1A_HUMAN (1-196): 3.67e-82: 244: 28.00		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269575 RAB1B_HUMAN (4-195): 1.12e-80: 240: 28.72		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		370406 RAB1B_HUMAN (4-195): 1.12e-80: 240: 28.72		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369336 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369329 RB11A_HUMAN (4-207): 7.68e-78: 234: 25.94		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377668 RAB1B_HUMAN (4-195): 1.12e-80: 240: 28.72		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		895531 RAB10_HUMAN (11-177): 3.9e-29: 109: 33.14		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		377213 RAB8A_HUMAN (1-203): 1.27e-79: 238: 24.76		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377227 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377223 RB11A_HUMAN (4-207): 7.68e-78: 234: 25.94		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		795594 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		NR4A2_HUMAN (23-501): 3.24e-98: 311: 23.30
+	Hs
		369288 RAB10_HUMAN (11-177): 3.9e-29: 109: 33.14		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377215 RAB10_HUMAN (11-177): 3.9e-29: 109: 33.14		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377084 RAB4A_HUMAN (11-169): 1.53e-27: 105: 34.57		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		414477 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		487305 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487282 RAB10_HUMAN (11-177): 3.9e-29: 109: 33.14		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59