HitPredict

Interactor 1: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Interactor 2: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 305
+	Hs
		919203 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		845228 RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13		SKI8_HUMAN (1-305): 2.86e-101: 300: 100.00
+	Hs
		903100 RAB1A_HUMAN (1-196): 3.67e-82: 244: 28.00		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		903508 RAB1B_HUMAN (4-195): 1.12e-80: 240: 28.72		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		894711 RAB8A_HUMAN (1-203): 1.27e-79: 238: 24.76		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		903101 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33