HitPredict

Interactor 1: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Interactor 2: RANB3 (Q9H6Z4)
Ran-binding protein 3 (RanBP3)
Gene: RANBP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	9637251, 11932251
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ran_BP1~Ras
Common GO terms	GO:0005634 - nucleus GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006611 - protein export from nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 216 Hs			1 567
+	At
		784991 RAN1_ARATH (1-216): 1.39e-95: 279: 73.52		NU50A_ARATH (79-536): 6.54e-41: 155: 14.50
+	Hs
		297829 RAB35_HUMAN (6-188): 1.31e-87: 258: 29.19		K0754_HUMAN (15-390): 1.08e-44: 172: 15.69
+	At
		784994 RAN1_ARATH (1-216): 1.39e-95: 279: 73.52		RBP1A_ARATH (354-566): 1e-37: 141: 21.65
+	At
		784989 RAN1_ARATH (1-216): 1.39e-95: 279: 73.52		RBP1B_ARATH (353-566): 1.01e-32: 126: 21.46
+	At
		785000 RAN2_ARATH (1-215): 1.36e-88: 261: 74.77		RBP1A_ARATH (354-566): 1e-37: 141: 21.65
+	At
		1210455 RAN3_ARATH (1-215): 9.1e-84: 249: 74.31		RBP1A_ARATH (354-566): 1e-37: 141: 21.65
+	At
		784998 RAN2_ARATH (1-215): 1.36e-88: 261: 74.77		RBP1B_ARATH (353-566): 1.01e-32: 126: 21.46
+	Ce
		184992 RAN_CAEEL (3-205): 3.44e-97: 283: 88.18		Q21021_CAEEL (281-564): 1.54e-21: 101: 16.44
+	Hs
		483392 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		RGPD1_HUMAN (237-548): 1.99e-36: 147: 17.30
+	Hs
		152774 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		RGPD8_HUMAN (246-547): 9.23e-36: 145: 16.72
+	Hs
		483422 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		RGPD2_HUMAN (237-548): 4.22e-35: 143: 17.30
+	Hs
		63882 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		RGPD3_HUMAN (246-548): 6.71e-35: 143: 16.03
+	At
		1210453 RAN3_ARATH (1-215): 9.1e-84: 249: 74.31		RBP1B_ARATH (353-566): 1.01e-32: 126: 21.46
+	Ce
		184995 RAN_CAEEL (3-205): 3.44e-97: 283: 88.18		Q86G90_CAEEL (281-564): 1.26e-17: 88.8: 15.19
+	Sc
		698835 GSP1_YEAST (1-214): 5.23e-83: 247: 80.56		YRB2_YEAST (177-510): 1.46e-30: 123: 20.24
+	Sc
		691616 GSP1_YEAST (1-214): 5.23e-83: 247: 80.56		NUP2_YEAST (120-512): 1.75e-28: 122: 14.25
+	Hs
		796725 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		RANG_HUMAN (355-549): 1.54e-34: 131: 17.73
+	Xl
		193796 RAN_XENLA (1-216): 7.81e-80: 239: 98.15		O42193_XENLA (355-555): 2.49e-28: 114: 18.01
+	Sc
		698847 GSP1_YEAST (1-214): 5.23e-83: 247: 80.56		YRB1_YEAST (330-515): 9.14e-24: 101: 18.75
+	Sp
		660086 SPI1_SCHPO (1-214): 1.23e-84: 251: 80.84		RANG_SCHPO (328-514): 3.85e-20: 91.1: 23.96