HitPredict

Interactor 1: RL23 (P62829)
Large ribosomal subunit protein uL14 (60S ribosomal protein L17) (60S ribosomal protein L23)
Gene: RPL23

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	21951318, 21182203
Identification Methods	affinity chromatography technology, cosedimentation through density gradient
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 530
+	Hs
		1158460 RM14_HUMAN (19-126): 6.25e-27: 99.4: 15.79		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		320196 RL23_HUMAN (1-140): 1.35e-62: 189: 100.00		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Mm
		509300 RL23_MOUSE (1-140): 1.35e-62: 189: 100.00		RARA_MOUSE (52-508): 5.87e-105: 324: 23.58
+	Hs
		487306 RL23_HUMAN (1-140): 1.35e-62: 189: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59