HitPredict

Interactor 1: RAP1A (P62834)
Ras-related protein Rap-1A (EC 3.6.5.2) (C21KG) (G-22K) (GTP-binding protein smg p21A) (Ras-related protein Krev-1)
Gene: RAP1A

Interactor 2: DUS22 (Q9NRW4)
Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x)
Gene: DUSP22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27432908, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 184 Hs			1 184
+	Hs
		304962 RB11B_HUMAN (4-173): 1.69e-70: 214: 30.41		DUS14_HUMAN (4-174): 4.51e-67: 205: 29.48
+	Hs
		919671 RAP1A_HUMAN (1-184): 5.85e-73: 219: 100.00		DUS9_HUMAN (5-170): 2.3e-61: 196: 33.53
+	Hs
		350588 RASK_HUMAN (1-184): 8.24e-56: 176: 54.45		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		349673 RASH_HUMAN (1-180): 7.38e-55: 173: 55.00		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		919654 RAP1A_HUMAN (1-184): 5.85e-73: 219: 100.00		DUS19_HUMAN (8-155): 6.84e-55: 174: 32.89
+	Hs
		349595 RASH_HUMAN (1-180): 7.38e-55: 173: 55.00		DUS9_HUMAN (5-170): 2.3e-61: 196: 33.53
+	Hs
		349778 RASH_HUMAN (1-180): 7.38e-55: 173: 55.00		DUS10_HUMAN (5-140): 1.61e-18: 84: 38.46
+	Hs
		349733 RASH_HUMAN (1-180): 7.38e-55: 173: 55.00		DUS12_HUMAN (5-156): 1.75e-18: 82.8: 32.34