HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 25275296, 16547522, 11724934, 12525502, 29191979, 18784070, 21113135, 21393245, 22902369, 11907583, 23871895
Identification Methods pull down, affinity chromatography technology, x-ray crystallography, two hybrid, surface plasmon resonance, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-C3HC4_3
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0032991 - protein-containing complex
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024