HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	26489670
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_5
Common GO terms	GO:0000209 - protein polyubiquitination GO:0004842 - ubiquitin-protein transferase activity GO:0006511 - ubiquitin-dependent protein catabolic process GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 1133
+	Hs
		829015 UBE2A_HUMAN (2-144): 1.41e-70: 210: 39.16		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		927756 UBE2B_HUMAN (2-144): 5.71e-70: 209: 37.76		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		896459 UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		919868 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1297369 UB2E2_HUMAN (4-146): 5.85e-75: 223: 65.73		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1282349 UB2E3_HUMAN (4-146): 3.05e-74: 221: 66.43		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		927778 UBE2B_HUMAN (2-144): 5.71e-70: 209: 37.76		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		896546 UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22		RC3H2_HUMAN (1-1107): 0: 1494: 51.72