HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: MEX3C (Q5U5Q3)
RNA-binding E3 ubiquitin-protein ligase MEX3C (EC 2.3.2.27) (RING finger and KH domain-containing protein 2) (RING finger protein 194) (RING-type E3 ubiquitin transferase MEX3C)
Gene: MEX3C

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	29643511, 30095198
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0005634 - nucleus GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 659
+	Hs
		50011 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		MEX3A_HUMAN (211-659): 1.69e-171: 501: 47.90
+	Hs
		282379 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		NEUL1_HUMAN (400-658): 8.37e-66: 228: 18.56
+	At
		715118 UBC8_ARATH (1-147): 8.9e-83: 241: 80.27		LUL3_ARATH (497-657): 9.27e-37: 143: 17.39
+	Hs
		849400 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		BIRC7_HUMAN (462-658): 9.84e-16: 80.3: 14.56
+	Hs
		919817 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		BIRC7_HUMAN (462-658): 9.84e-16: 80.3: 14.56
+	Hs
		849322 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		BIRC2_HUMAN (586-658): 6.42e-14: 77.2: 23.29
+	Hs
		919722 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		BIRC2_HUMAN (586-658): 6.42e-14: 77.2: 23.29
+	Hs
		849321 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		BIRC3_HUMAN (603-658): 6.9e-14: 76.8: 25.00
+	Hs
		919721 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		BIRC3_HUMAN (603-658): 6.9e-14: 76.8: 25.00
+	Hs
		230183 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		MGRN1_HUMAN (588-657): 5.04e-12: 71: 25.35
+	Hs
		1298970 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		BIRC8_HUMAN (470-658): 6.67e-13: 70.6: 14.55
+	Hs
		1282543 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		MUL1_HUMAN (596-658): 5.36e-12: 69.9: 26.98
+	Hs
		230126 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		MGRN1_HUMAN (588-657): 5.04e-12: 71: 25.35
+	Hs
		230132 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		MGRN1_HUMAN (588-657): 5.04e-12: 71: 25.35
+	Hs
		849413 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		BIRC8_HUMAN (470-658): 6.67e-13: 70.6: 14.55
+	Hs
		919831 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		BIRC8_HUMAN (470-658): 6.67e-13: 70.6: 14.55
+	Hs
		849387 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		RFFL_HUMAN (583-658): 5.05e-12: 69.9: 23.68
+	Hs
		849394 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		MUL1_HUMAN (596-658): 5.36e-12: 69.9: 26.98
+	Hs
		919804 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		RFFL_HUMAN (583-658): 5.05e-12: 69.9: 23.68
+	Hs
		919811 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		MUL1_HUMAN (596-658): 5.36e-12: 69.9: 26.98