HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: TRI46 (Q7Z4K8)
Tripartite motif-containing protein 46 (Gene Y protein) (GeneY) (Tripartite, fibronectin type-III and C-terminal SPRY motif protein)
Gene: TRIM46

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	29643511
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 759
+	Hs
		175730 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI18_HUMAN (24-750): 1.62e-116: 368: 21.15
+	Hs
		175664 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI18_HUMAN (24-750): 1.62e-116: 368: 21.15
+	Hs
		1151762 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		Q6GX22_HUMAN (24-749): 3.27e-111: 354: 18.75
+	Hs
		919761 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI67_HUMAN (27-744): 1.48e-106: 345: 19.62
+	Hs
		1356055 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM1_HUMAN (85-749): 6.26e-101: 329: 19.46
+	Hs
		1052807 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI25_HUMAN (27-748): 5.47e-85: 283: 12.52
+	Hs
		919727 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI25_HUMAN (27-748): 5.47e-85: 283: 12.52
+	Hs
		1318738 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM2_HUMAN (141-717): 4.1e-74: 257: 12.05
+	Hs
		1333889 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI45_HUMAN (32-533): 6.82e-65: 228: 17.18
+	Hs
		1317493 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI54_HUMAN (10-428): 1.15e-61: 212: 21.50
+	Hs
		1336390 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI39_HUMAN (24-541): 1.21e-35: 144: 10.45
+	Hs
		1318719 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM5_HUMAN (19-144): 2.82e-29: 124: 20.31
+	Hs
		584923 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		RO52_HUMAN (20-149): 3.56e-27: 117: 15.15
+	Mm
		919925 UB2D2_MOUSE (1-147): 9.5e-83: 241: 100.00		TRI17_MOUSE (25-168): 6.59e-27: 117: 14.74
+	Hs
		1318358 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM8_HUMAN (127-398): 2.92e-25: 112: 22.14
+	Hs
		537142 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI27_HUMAN (19-149): 3.94e-25: 112: 21.32
+	Hs
		536779 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI27_HUMAN (19-149): 3.94e-25: 112: 21.32
+	Hs
		1285831 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI43_HUMAN (326-728): 2.09e-15: 81.2: 12.29
+	Hs
		262201 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM3_HUMAN (14-149): 4.03e-12: 71.7: 16.67
+	Hs
		262167 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRIM3_HUMAN (14-149): 4.03e-12: 71.7: 16.67