HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.845

Property	Details
Experiments	11782429, 14990566, 22889411
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 728
+	Hs
		1252560 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		919784 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		LNX2_HUMAN (3-728): 5.7e-116: 366: 45.21
+	Hs
		919911 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		PZRN3_HUMAN (193-398): 3.72e-11: 68.9: 15.24
+	Mm
		896584 UBE2N_MOUSE (4-147): 7.67e-69: 206: 47.22		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40