HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: TRI41 (Q8WV44)
E3 ubiquitin-protein ligase TRIM41 (EC 2.3.2.27) (RING finger-interacting protein with C kinase) (RINCK) (Tripartite motif-containing protein 41)
Gene: TRIM41

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	17893151
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016567 - protein ubiquitination GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 630
+	Hs
		1336390 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI39_HUMAN (133-630): 1.99e-142: 425: 31.09
+	Hs
		1318719 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM5_HUMAN (6-150): 3.22e-22: 102: 19.46
+	Hs
		919822 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI11_HUMAN (1-130): 1.56e-22: 103: 26.81
+	Hs
		584923 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		RO52_HUMAN (7-141): 1.35e-20: 97.4: 21.53
+	Hs
		537142 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI27_HUMAN (7-127): 8.35e-20: 95.1: 18.80
+	Hs
		1285831 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI43_HUMAN (6-142): 9.18e-20: 94.3: 19.57
+	Hs
		536779 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI27_HUMAN (7-127): 8.35e-20: 95.1: 18.80
+	Hs
		1377469 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI17_HUMAN (9-142): 4.54e-19: 92.4: 24.44
+	Hs
		919816 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI43_HUMAN (6-142): 9.18e-20: 94.3: 19.57
+	Hs
		919712 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI26_HUMAN (7-217): 4.05e-19: 93.1: 16.90
+	Hs
		135045 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI38_HUMAN (7-150): 1.67e-18: 90.8: 18.75
+	Hs
		919846 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI34_HUMAN (6-150): 4.11e-19: 92.7: 17.33
+	Mm
		919925 UB2D2_MOUSE (1-147): 9.5e-83: 241: 100.00		TRI17_MOUSE (9-130): 4.54e-19: 92.4: 21.90
+	Hs
		1204911 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI50_HUMAN (10-134): 7.23e-18: 88.9: 16.92
+	Hs
		135019 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI38_HUMAN (7-150): 1.67e-18: 90.8: 18.75
+	Hs
		919773 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI50_HUMAN (10-134): 7.23e-18: 88.9: 16.92
+	Hs
		1357712 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI35_HUMAN (3-147): 4.52e-17: 86.6: 16.55
+	Hs
		1313765 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI62_HUMAN (14-139): 1.3e-16: 85: 19.42
+	Hs
		919841 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI62_HUMAN (14-139): 1.3e-16: 85: 19.42
+	Hs
		1354526 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI10_HUMAN (7-150): 1.19e-15: 82: 17.45