HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: MARH5 (Q9NX47)
E3 ubiquitin-protein ligase MARCHF5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (Mitochondrial ubiquitin ligase) (MITOL) (RING finger protein 153) (RING-type E3 ubiquitin transferase MARCHF5)
Gene: MARCHF5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.744

Property	Details
Experiments	29643511, 23727017, 31368599, 31819032, 35459736, 22308378, 19741096
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000209 - protein polyubiquitination GO:0051865 - protein autoubiquitination GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 278
+	Hs
		849461 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		MARH5_HUMAN (1-278): 1.37e-162: 454: 100.00
+	Hs
		895930 UB2D3_HUMAN (1-147): 1.54e-81: 238: 97.28		MARH5_HUMAN (1-278): 1.37e-162: 454: 100.00
+	Hs
		1282354 UB2E3_HUMAN (4-146): 3.05e-74: 221: 66.43		MARH5_HUMAN (1-278): 1.37e-162: 454: 100.00
+	Hs
		851894 UB2E1_HUMAN (4-146): 8.81e-73: 217: 65.73		MARH5_HUMAN (1-278): 1.37e-162: 454: 100.00
+	Hs
		896552 UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22		MARH5_HUMAN (1-278): 1.37e-162: 454: 100.00
+	Dm
		715100 UBE2N_DROME (4-147): 8.8e-45: 145: 49.31		Q9VB61_DROME (10-278): 9.68e-143: 404: 39.71