Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1
Interactor 2: CDC6 (Q99741)
Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6)
Gene: CDC6
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.60 | 0.60 | 0.604 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21041660 |
| Identification Methods | pull down, affinity chromatography technology, enzymatic study, anti bait coimmunoprecipitation, protein kinase assay |
| Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000922 - spindle pole GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 3 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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| + | Ce |   |
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| + | Sp |  |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
