HitPredict

Interactor 1: RS25 (P62851)
Small ribosomal subunit protein eS25 (40S ribosomal protein S25)
Gene: RPS25

Interactor 2: RIOK1 (Q9BRS2)
Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)
Gene: RIOK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	21081503, 36321656
Identification Methods	affinity chromatography technology, x-ray crystallography
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ribosomal_S25~RIO1
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0042274 - ribosomal small subunit biogenesis
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 125 Hs			1 568
+	Hs
		152954 RS25_HUMAN (1-125): 3.79e-46: 147: 100.00		RIOK3_HUMAN (1-436): 0: 535: 34.96
+	Sc
		1015295 RS25A_YEAST (10-113): 8.17e-30: 105: 44.23		RIO1_YEAST (109-546): 5.16e-116: 354: 36.56
+	Sc
		770080 RS25A_YEAST (10-113): 8.17e-30: 105: 44.23		RIO2_YEAST (168-550): 2.83e-67: 226: 17.47
+	Sc
		470668 RS25B_YEAST (10-112): 6.43e-29: 102: 43.69		RIO2_YEAST (168-550): 2.83e-67: 226: 17.47