Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: GBG5 (P63218)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
Gene: GNG5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 33961781, 8636150, 19168127, 35271311, 35235311, 34349018, 37071682, 12782285, 25416956
Identification Methods affinity chromatography technology, two hybrid, cross-linking study, pull down, anti tag coimmunoprecipitation, mammalian protein protein interaction trap
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains G-gamma~WD40
Common GO terms GO:0003924 - GTPase activity
GO:0005834 - heterotrimeric G-protein complex
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0007186 - G protein-coupled receptor signaling pathway
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 340
Hs

1 68
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Last updated: 15 Jul 2024