HitPredict

Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: VAC14 (Q08AM6)
Protein VAC14 homolog (Tax1-binding protein 2)
Gene: VAC14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 782
+	Hs
		921660 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		IPO4_HUMAN (50-499): 4.04e-16: 84.9: 14.99
+	Hs
		921634 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74
+	Hs
		127239 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		IPO5_HUMAN (3-537): 9.42e-12: 71: 12.98
+	Hs
		268815 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		SF3B1_HUMAN (8-584): 5.41e-31: 133: 9.71
+	Hs
		268646 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		SF3B1_HUMAN (8-584): 5.41e-31: 133: 9.71
+	Hs
		903383 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		IPO4_HUMAN (50-499): 4.04e-16: 84.9: 14.99
+	Hs
		903348 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74
+	Hs
		903400 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		GCN1_HUMAN (3-394): 6.91e-14: 78: 11.84
+	Hs
		127234 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		IPO5_HUMAN (3-537): 9.42e-12: 71: 12.98
+	Hs
		196925 PRP4_HUMAN (51-253): 1.06e-12: 70.5: 25.85		SF3B1_HUMAN (8-584): 5.41e-31: 133: 9.71
+	Hs
		197051 PRP4_HUMAN (51-253): 1.06e-12: 70.5: 25.85		CAND1_HUMAN (4-541): 8.72e-15: 80.7: 11.74