HitPredict

Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Hs			1 530
+	Hs
		921671 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		560885 GBB3_HUMAN (1-340): 1.83e-104: 311: 83.24		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369344 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369342 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370470 GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369932 WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		320198 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Hs
		320197 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Hs
		320228 GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Hs
		320167 GBB3_HUMAN (1-340): 1.83e-104: 311: 83.24		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Hs
		377230 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377229 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		369305 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		488008 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		RARA_HUMAN (52-505): 3.54e-105: 324: 23.74
+	Hs
		782513 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Mm
		903664 WDR5_MOUSE (4-211): 4.16e-56: 187: 20.93		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Hs
		487309 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487308 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		1334929 GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88		NR2E1_HUMAN (149-408): 2.63e-35: 137: 31.82
+	Hs
		487288 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59