HitPredict

Interactor 1: RPAB5 (P62875)
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RNA polymerase II 7.6 kDa subunit) (RPB7.6) (RPB10 homolog)
Gene: POLR2L

Interactor 2: GPN2 (Q9H9Y4)
GPN-loop GTPase 2 (ATP-binding domain 1 family member B)
Gene: GPN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 67 Hs			1 310
+	Hs
		921190 RPAB5_HUMAN (1-67): 3.73e-35: 114: 100.00		GPN3_HUMAN (10-261): 1.68e-124: 359: 41.73
+	Sc
		604716 RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06		GPN3_YEAST (10-269): 5.62e-115: 334: 37.50
+	Hs
		921170 RPAB5_HUMAN (1-67): 3.73e-35: 114: 100.00		GPN1_HUMAN (2-197): 1.18e-97: 294: 27.27
+	Sc
		604701 RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06		GPN1_YEAST (13-272): 8.25e-85: 261: 22.68