HitPredict

Interactor 1: RPAB5 (P62875)
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RNA polymerase II 7.6 kDa subunit) (RPB7.6) (RPB10 homolog)
Gene: POLR2L

Interactor 2: RPA12 (Q9P1U0)
DNA-directed RNA polymerase I subunit RPA12 (DNA-directed RNA polymerase I subunit H) (Zinc ribbon domain-containing protein 1)
Gene: POLR1H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001054 - RNA polymerase I activity GO:0005654 - nucleoplasm GO:0005736 - RNA polymerase I complex GO:0008270 - zinc ion binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 67 Hs			1 126
+	Hs
		738841 RPAB5_HUMAN (1-67): 3.73e-35: 114: 100.00		RPB9_HUMAN (11-124): 2.03e-35: 119: 16.95
+	Hs
		921195 RPAB5_HUMAN (1-67): 3.73e-35: 114: 100.00		RPC10_HUMAN (16-124): 3.48e-29: 103: 22.12
+	Sc
		604656 RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06		RPB9_YEAST (15-125): 6.62e-32: 110: 21.43
+	Sc
		604713 RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06		RPC10_YEAST (16-125): 7.49e-30: 105: 26.72
+	Sc
		604663 RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06		RPA12_YEAST (12-126): 7.84e-27: 98.3: 33.87
+	Dm
		1362544 RPAB5_DROME (1-67): 1.71e-35: 115: 92.54		Q9VXS6_DROME (28-124): 6.97e-17: 73.6: 12.00