Interactor 1: RBX1 (P62877)
E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (E3 ubiquitin-protein transferase RBX1) (Protein ZYP) (RING finger protein 75) (RING-box protein 1) (Rbx1) (Regulator of cullins 1) (ROC1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed (E3 ubiquitin-protein transferase RBX1, N-terminally processed)]
Gene: RBX1

Interactor 2: GLMN (Q92990)
Glomulin (FK506-binding protein-associated protein) (FAP) (FKBP-associated protein)
Gene: GLMN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.955

The method score is based on:

Property Details
Experiments 22405651, 22748924, 30349055, 32296183, 33961781, unassigned1304
Identification Methods affinity chromatography technology, pull down, two hybrid, fluorescent resonance energy transfer, two hybrid array, two hybrid prey pooling approach, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Kinetochor_Ybp2~zf-rbx1
Common GO terms GO:0005737 - cytoplasm
GO:0031461 - cullin-RING ubiquitin ligase complex
GO:0031462 - Cul2-RING ubiquitin ligase complex
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0031464 - Cul4A-RING E3 ubiquitin ligase complex
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 108
Hs

1 594
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024