HitPredict

Interactor 1: RBX1 (P62877)
E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (E3 ubiquitin-protein transferase RBX1) (Protein ZYP) (RING finger protein 75) (RING-box protein 1) (Rbx1) (Regulator of cullins 1) (ROC1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed (E3 ubiquitin-protein transferase RBX1, N-terminally processed)]
Gene: RBX1

Interactor 2: KLHL9 (Q9P2J3)
Kelch-like protein 9
Gene: KLHL9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33504946
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0031463 - Cul3-RING ubiquitin ligase complex GO:0097602 - cullin family protein binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 108 Hs			1 617
+	Hs
		921464 RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00		KLHL3_HUMAN (401-615): 7.27e-55: 198: 25.58
+	Hs
		921260 RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00		KEAP1_HUMAN (397-615): 2.34e-54: 197: 28.25
+	Hs
		299513 RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00		KLH18_HUMAN (430-616): 6.54e-42: 161: 24.34
+	Hs
		921453 RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00		KLHL8_HUMAN (446-615): 1.79e-35: 143: 20.47
+	Hs
		921456 RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00		KLH13_HUMAN (448-615): 3.91e-30: 127: 20.59
+	Hs
		921393 RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00		KLH15_HUMAN (450-617): 1.27e-20: 98: 18.45
+	Hs
		921308 RBX1_HUMAN (1-108): 5.69e-51: 157: 100.00		KLH24_HUMAN (478-616): 2.39e-19: 94.1: 17.73