Interactor 1: RBX1 (P62878)
E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (E3 ubiquitin-protein transferase RBX1) (RING finger protein 75) (RING-box protein 1) (Rbx1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed]
Gene: RBX1

Interactor 2: CUL4A (Q3TCH7)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 19037258
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~zf-rbx1, Cullin_Nedd8~zf-rbx1
Common GO terms GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0006974 - DNA damage response
GO:0007283 - spermatogenesis
and 8 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 108
Mm

1 759
+ Hs
+ Hs
+ Mm
+ Dm
+ At
+ At
+ At
+ Hs
+ Dm
+ Hs
+ Mm
+ At
+ Hs
+ Dm
+ Sp
+ Dm
+ Sp
+ Ce
+ Hs
+ Ce

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Last updated: 15 Jul 2024