Interactor 1: RBX1 (P62878)
E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (E3 ubiquitin-protein transferase RBX1) (RING finger protein 75) (RING-box protein 1) (Rbx1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed]
Gene: RBX1

Interactor 2: FBXW8 (Q8BIA4)
F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8)
Gene: FBXW8

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 16880526
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex
GO:0031467 - Cul7-RING ubiquitin ligase complex
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 108
Mm

1 598
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Sp
+ Hs
+ Sc
+ Hs

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Last updated: 15 Jul 2024