HitPredict

Interactor 1: GBB2 (P62879)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)
Gene: GNB2

Interactor 2: UBE2U (Q5VVX9)
Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U)
Gene: UBE2U

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~WD40
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 321
+	Hs
		921784 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33
+	Hs
		849304 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		UB2D1_HUMAN (4-153): 1.02e-75: 230: 30.00
+	Hs
		919704 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		UB2D2_HUMAN (4-153): 8.78e-76: 230: 34.67
+	Hs
		895772 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		UB2D3_HUMAN (4-153): 1.55e-74: 227: 34.00
+	Hs
		135929 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		UBE2C_HUMAN (9-145): 2.39e-20: 88.2: 35.77