HitPredict

Interactor 1: GBB2 (P62879)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)
Gene: GNB2

Interactor 2: WDR36 (Q8NI36)
WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP)
Gene: WDR36

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 951
+	Hs
		1246459 SNR40_HUMAN (130-340): 6.93e-58: 192: 23.36		WDR36_HUMAN (1-951): 0: 622: 100.00
+	Hs
		1246488 NLE1_HUMAN (2-124): 8.9e-29: 117: 26.77		WDR36_HUMAN (1-951): 0: 622: 100.00
+	Hs
		1016312 SNR40_HUMAN (130-340): 6.93e-58: 192: 23.36		TBL3_HUMAN (2-361): 3.23e-60: 222: 14.88
+	Sc
		630844 NLE1_YEAST (2-297): 6.96e-77: 246: 19.20		NLE1_YEAST (29-317): 5.43e-43: 166: 13.08
+	Hs
		921751 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		NLE1_HUMAN (42-150): 2.8e-12: 72.3: 9.74
+	Hs
		903349 WDR5B_HUMAN (89-340): 4.94e-82: 253: 25.39		WDR5_HUMAN (32-232): 5.32e-20: 94.4: 17.89
+	Hs
		1240442 POC1B_HUMAN (126-340): 2.42e-64: 212: 20.37		POC1A_HUMAN (123-363): 8.34e-33: 133: 15.39
+	Hs
		1288390 SNR40_HUMAN (130-340): 6.93e-58: 192: 23.36		WDR3_HUMAN (379-700): 3.49e-29: 127: 12.06
+	Hs
		903174 WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92		TBL3_HUMAN (2-361): 3.23e-60: 222: 14.88
+	Hs
		1288388 SNR40_HUMAN (130-340): 6.93e-58: 192: 23.36		PRP19_HUMAN (528-703): 1.05e-20: 98.7: 16.37
+	Hs
		725410 WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92		COPB2_HUMAN (325-850): 2.34e-52: 200: 7.88
+	Hs
		903428 SNR40_HUMAN (130-340): 6.93e-58: 192: 23.36		WDR5_HUMAN (32-232): 5.32e-20: 94.4: 17.89
+	Dm
		1358845 WDS_DROME (4-215): 7e-53: 179: 20.18		WDS_DROME (613-748): 4.16e-21: 98.2: 18.98
+	Hs
		793026 LIS1_HUMAN (258-340): 1.53e-19: 90.5: 22.89		KTNB1_HUMAN (331-633): 1.83e-28: 124: 16.34
+	Hs
		903551 NLE1_HUMAN (2-124): 8.9e-29: 117: 26.77		WDR5_HUMAN (32-232): 5.32e-20: 94.4: 17.89
+	Hs
		1346954 NLE1_HUMAN (2-124): 8.9e-29: 117: 26.77		NLE1_HUMAN (42-150): 2.8e-12: 72.3: 9.74
+	Hs
		863397 WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92		COPA_HUMAN (2-263): 7.56e-21: 101: 9.83
+	Hs
		792949 LIS1_HUMAN (258-340): 1.53e-19: 90.5: 22.89		WDR5_HUMAN (32-232): 5.32e-20: 94.4: 17.89
+	Hs
		903077 WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92		WDR5_HUMAN (32-232): 5.32e-20: 94.4: 17.89