HitPredict

Interactor 1: RL11 (P62913)
Large ribosomal subunit protein uL5 (60S ribosomal protein L11) (CLL-associated antigen KW-12)
Gene: RPL11

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0031625 - ubiquitin protein ligase binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 178 Hs			1 768
+	Hs
		923004 RL11_HUMAN (1-178): 2.2e-91: 265: 100.00		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		923005 RL11_HUMAN (1-178): 2.2e-91: 265: 100.00		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		923001 RL11_HUMAN (1-178): 2.2e-91: 265: 100.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		923002 RL11_HUMAN (1-178): 2.2e-91: 265: 100.00		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		923138 RL11_HUMAN (1-178): 2.2e-91: 265: 100.00		CUL5_HUMAN (25-768): 0: 597: 23.77