HitPredict

Interactor 1: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Interactor 2: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24999758
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pro_isomerase~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 656
+	Hs
		967515 PPIE_HUMAN (2-163): 2.08e-88: 262: 67.28		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		614297 PPIB_HUMAN (2-165): 9.46e-88: 257: 63.64		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		726728 PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		727096 PPIE_HUMAN (2-163): 2.08e-88: 262: 67.28		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		203502 PPIH_HUMAN (2-164): 1.38e-84: 247: 53.85		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		358493 PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00		CO1A1_HUMAN (2-506): 1.09e-18: 92.9: 14.74
+	Hs
		358476 PPIB_HUMAN (2-165): 9.46e-88: 257: 63.64		CO1A1_HUMAN (2-506): 1.09e-18: 92.9: 14.74
+	Hs
		436027 PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00		CO1A2_HUMAN (4-301): 3.82e-16: 84.9: 12.95