HitPredict

Interactor 1: AP2B1 (P62944)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 937 Rn			1 810
+	Rn
		1144175 Q66HM2_RAT (11-932): 0: 590: 16.38		UBC_RAT (1-810): 0: 1000: 100.00
+	Hs
		475594 AP2B1_HUMAN (1-937): 0: 926: 100.00		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		321470 AP2A1_HUMAN (11-932): 0: 634: 16.97		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		302094 AP2A2_HUMAN (11-933): 0: 600: 16.99		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475514 COPB_HUMAN (8-927): 0: 561: 12.47		UBC_HUMAN (1-533): 0: 662: 99.81
+	Zm
		111864 K7VAA4_MAIZE (13-808): 1.26e-178: 541: 15.95		Q42415_MAIZE (305-801): 0: 594: 92.35
+	At
		286688 APBLC_ARATH (3-936): 0: 756: 56.46		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1092397 APBLB_ARATH (3-936): 0: 750: 56.14		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Mm
		477012 AP2B1_MOUSE (1-937): 0: 926: 99.89		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		397894 AP2B1_HUMAN (1-937): 0: 926: 100.00		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69
+	Zm
		111863 K7VAA4_MAIZE (13-808): 1.26e-178: 541: 15.95		Q41754_MAIZE (457-801): 2.42e-135: 408: 90.73
+	At
		1092398 COPB1_ARATH (6-919): 0: 562: 13.63		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1091811 AP2A2_ARATH (13-934): 0: 554: 15.90		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1013363 COPG_ARATH (3-933): 4.18e-175: 533: 14.06		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Mm
		476683 AP2A1_MOUSE (11-932): 0: 633: 17.04		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		321462 AP2A1_HUMAN (11-932): 0: 634: 16.97		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69
+	Mm
		476684 AP2A2_MOUSE (11-932): 0: 596: 16.50		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		302089 AP2A2_HUMAN (11-933): 0: 600: 16.99		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69
+	Hs
		863195 COPB_HUMAN (8-927): 0: 561: 12.47		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Zm
		22940 A0A1D6NI64_MAIZE (12-741): 7.59e-175: 531: 31.18		A0A1D6I4G6_MAIZE (2-76): 1.16e-23: 100: 61.33